MANGO
The Mammalian Adult Neurogenesis Gene Ontology
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Proliferation
Differentiation
Migration
Neuritogenesis
Axonogenesis
Dendritogenesis
Maturation
Survival
Expression
Numbers
Function
Adult neurogenic cell
Precursor
Vertical astrocyte (Type 0)
Stem cell (Type 1)
Progenitor
Undetermined progenitor (Type 2a)
Late progenitor
Determined progenitor (Type 2b)
Neuroblast-like cell (Type 3)
New neuron
Immature neuron
Early immature neuron
Late immature neuron
Mature neuron
BrdU immunoreactive cell
Doublecortin immunoreactive cell
Calretinin immunoreactive cell
Calbindin immunoreactive cell
Astrocyte
Oligodendrocyte
Granule cell neuron
+
±
−
* Gene or protein expression
** Protein manipulation
*** Gene manipulation
Guinea pig
Human
Monkey
Mouse
Rat
Other
In vivo
Ex vivo
In vitro
Gene
Process / Outcome
Cell stage / Marker
Effect
Evidence
Species
Type
Reference
Abca2
Expression
Doublecortin immunoreactive cell
+
*
Mouse
in vivo
Broccardo (2006)
Ace2
Proliferation
Precursor
±
***
Mouse
in vivo
Klempin (2018)
Ache
Survival
Immature neuron
−
***
Mouse
in vivo
Cohen (2008)
Ache
Expression
Precursor
+
***
Mouse
in vivo
Cohen (2008)
Ache
Proliferation
Precursor
−
***
Mouse
in vivo
Cohen (2008)
Ache
Expression
New neuron
+
***
Mouse
in vivo
Cohen (2008)
Ache
Numbers
New neuron
−
**
Rat
in vivo
Mohapel (2005)
Ache
Numbers
New neuron
−
**
Mouse
in vivo
Kaneko (2006)
Ache
Numbers
New neuron
−
**
Rat
in vivo
Kotani (2006)
Ache
Expression
Granule cell neuron
+
***
Mouse
in vivo
Cohen (2008)
Ache
Numbers
New neuron
−
***
Mouse
in vivo
Cohen (2008)
Ache
Proliferation
Precursor
−
**
Rat
in vivo
Mohapel (2005)
Ache
Survival
New neuron
−
**
Mouse
in vivo
Kaneko (2006)
Ache
Proliferation
Precursor
±
**
Mouse
in vivo
Kaneko (2006)
Ache
Proliferation
Precursor
±
**
Rat
in vivo
Kotani (2006)
Ackr3
Expression
Mature neuron
+
*
Rat
in vivo
Schönemeier (2008)
Adcyap1
Proliferation
Precursor
±
***
Mouse
in vivo
Ago (2011)
Adcyap1
Numbers
BrdU immunoreactive cell
+
**
Mouse
in vivo
Ohta (2006)
Adcyap1
Numbers
New neuron
±
***
Mouse
in vivo
Ago (2011)
Adcyap1
Numbers
Doublecortin immunoreactive cell
+
**
Mouse
in vivo
Ohta (2006)
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